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MSU College of Osteopathic Medicine

Objectives: Cytopathology

1. For normal neurons, understand structure and function of axons, dendrites and cell bodies. (review)

2. Understand the basic events of synaptic transmission and characteristics of the major neurotransmitters. (review)

3. Know the characteristics of basic pathological reactions of neurons, including necrosis, apoptosis, ischemic cell change, neuronal degeneration, central chromatolysis, neuronal inclusions.

4. Understand characteristics of normal astrocytes, and changes occurring in gliosis.

5. Understand characteristics of normal oligodendrocytes, and general pathological reactions.

6. Understand characteristics of normal ependymal cells.

7. Understand characteristics of normal microglia (CNS representatives of the reticuloendothelial system), and general pathological reactions.