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Objectives: CNS Neoplasms

1. Contrast neoplasms of the nervous system in children and adults:

A. type
B. location
C. primary or metastatic in nature

2. Discuss general symptoms of nervous system neoplasms and the diagnostic studies used most frequently.  List signs and symptoms secondary to space-occupying effects of supratentorial and infratentorial tumors and discuss pathogenesis of these clinical signs.

3. Describe remote effects of neoplasms on the nervous system (paraneoplastic syndromes) and give examples.

4. For the 3 primary central nervous system neoplasms found in children (pilocytic astrocytoma, ependymoma, medulloblastoma):

A. list sites where found
B. list signs and symptoms
C. describe gross and microscopic lesions, and potential for spread in CSF
D. list cell of origin
E. classify as benign or malignant, and understand prognosis

For retinoblastoma and neuroblastoma, describe locations and general features.
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