Home MSU College of Human Medicine
MSU College of Osteopathic Medicine

Objectives: CNS Trauma

1. Describe the mechanisms by which the brain is injured following closed-head injury.

2. List delayed sequelae/complications of CNS trauma.

3. Compare hemorrhage into epidural, subdural and subarachnoid spaces:

  • List arteries and/or veins and CNS structures involved.
  • Describe the pathogenesis of the lesions.
  • Describe clinical manifestations and relate the time of injury to symptoms and recovery or death.
  • Describe the gross and microscopic appearance of lesions.
  • Discuss CSF findings.

4. Define concussion, discuss associated clinical and pathological changes.

5. Discuss contusions with respect to pathogenesis, pathology, and location.

6. Discuss causes, most common locations, pathology and clinical signs of spinal cord trauma. Describe the types of neurological deficits and locations of lesions due to Wallerian degeneration produced by transection of the cord.