III. Meningitis (Leptomeningitis)
C. Pathological changes (cont):
3. Chronic meningitis - caused by fungi (e.g., candidiasis, cryptococcosis), tubercle bacillus (tuberculosis), T. pallidum (syphilis):
- Exudate, mononuclear infiltrate with lymphocytes, mononuclear cells, small tubercles (caseous necrosis surrounded by epithelioid cells and giant cells, peripheral ring of lymphocytes)
- Localized over base of brain
- Vasculitis common
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