I. General Principles

G. Sequelae & Complications: 

Sequelae of a CNS infection depend on the pathogenesis and location of lesions.  Examples include:

• Hydrocephalus after obstruction of CSF flow in leptomeningitis
• Permanent damage to cranial nerves
• Focal and generalized signs due to neuronal destruction, e.g. seizures, movement disorders, mental retardation
• Thrombosis due to vasculitis
• Consequences of increased intracranial pressure due to edema or expanding mass lesions