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MSU College of Osteopathic Medicine

I. General Principles

G. Sequelae & Complications

Sequelae of a CNS infection depend on the pathogenesis and location of lesions.  Examples include:

  • Hydrocephalus after obstruction of CSF flow in leptomeningitis
  • Permanent damage to cranial nerves
  • Focal and generalized signs due to neuronal destruction, e.g. seizures, movement disorders, mental retardation
  • Thrombosis due to vasculitis
  • Consequences of increased intracranial pressure due to edema or expanding mass lesions