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MSU College of Osteopathic Medicine

Objectives: Demyelinating Disorders

1. For multiple sclerosis, describe the pathogenesis, type and location of pathological changes; signs and symptoms; diagnostic criteria including CSF findings; and course of disease:

2. Know that Guillain-Barre Syndrome is a demyelinating disease of the peripheral nervous system, in contrast to multiple sclerosis, which is characterized by demyelination in the CNS.